Emergency Drug Review
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Moral distress is an all too common and frustrating aspect of critical care nursing. Just consider the following case scenarios.
NT-pro B-Type Natriuretic Peptide (NT-pro BNP): Evidence is emerging to suggest that measurement of BNP as a prognostic marker may be a powerful tool. The St Paul’s Hospital Heart Transplant Program uses NT-proBNP (a form of BNP) in conjunction with the measurements outlined in CCS Guidelines to aid in transplant listing or delisting decisions. Currently, a level of 1,500pg/ml has been identified. Levels greater than this has been associated with significantly increased mortality in heart failure patients[2-5]
Interesting site for:
The information provided here is for educational and informational purposes only...
It shouldn't be used in either diagnosis or treatment .
Medicine
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The physicians in the I.C.U. at St. Paul's Hospital are engaged in world leading research. We will be adding articles for the staff's benefit to inform them as to what these physicians are currently working on.
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GENERAL INFORMATION:
High Frequency Oscillatory Ventilation (HFO) is a ventilatory strategy that employs very small tidal volumes (often less than anatomic dead space) combined with very fast rates or frequencies (where 1 Hertz or Hz = 60cycles/min).
The Sensormedics 3100B high frequency oscillator consists of a continuous positive airway pressure circuit with an integrated motor-driven piston/diaphragm for generating the oscillations. There is active inspiration as well as active expiration on the oscillator.
Gas transport during HFO is thought to be as a result of several factors: molecular diffusion, direct alveolar ventilation (bulk gas flow to the proximal alveoli), net convective transport caused by asymmetric gas-velocity profiles, improved gas mixing caused by Taylor dispersion in turbulent flow, pendelluft, and cardiogenic mixing.
In HFO, alveolar ventilation (and thus CO2 elimination) is dependent on frequency and tidal volume, but relatively independent of lung volume. Oxygenation is “uncoupled” from ventilation; that is, it is proportional to mean airway pressure and lung volume.
And an interesting article from Stanford:
Drug Monographs
PLEASE BE AWARE THAT THESE ARE PROVIDED EXTERNALLY FROM LONDON HEALTH SCIENCES AS A REFERENCE ONLY.